SITANOW-M 1000

Description:

• SITANOW-M 1000 combines sitagliptin 50 mg and metformin hydrochloride 1000 mg in a single oral tablet, designed to enhance glycemic control in adults with type 2 diabetes mellitus. This formulation leverages the complementary mechanisms of a DPP-4 inhibitor and a biguanide to address multiple pathophysiological aspects of diabetes.
• As one of the trusted sitagliptin tablets 50mg manufacturer, we deliver consistent quality and bioavailability.
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• We’re also recognized among established metformin tablets wholesalers, supporting hospitals, pharmacies, and institutional buyers.
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Key Features:

• Integrates sitagliptin's incretin-enhancing effects with metformin's insulin sensitization to improve overall glycemic control.
• Demonstrates significant HbA1c reduction and supports postprandial glucose regulation.
• Associated with weight neutrality or modest weight loss, beneficial for overweight patients.
• Once-daily dosing simplifies the regimen, potentially improving patient adherence.
• Suitable for patients requiring intensified therapy beyond monotherapy.

Usage Guidelines:

• Administer once daily with meals to minimize gastrointestinal side effects.
• Appropriate for adults with type 2 diabetes inadequately controlled with metformin alone or those initiating combination therapy.
• Regular monitoring of renal function is recommended to ensure safe metformin use.

Safety Profile:

• Common side effects may include gastrointestinal discomfort such as nausea or diarrhea.
• Not recommended for patients with type 1 diabetes, diabetic ketoacidosis, or severe renal impairment.
• Caution advised in patients with hepatic dysfunction or those at risk for lactic acidosis.

Uses / Indications: As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.